Kyle S McCommis Selected Research

Monocarboxylic Acid Transporters

11/2020	Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice.
5/2020	NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis.
1/2017	Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis.
8/2016	An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion.

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Kyle S McCommis Research Topics

Disease

8	Non-alcoholic Fatty Liver Disease 01/2021 - 07/2014
5	Obesity 01/2022 - 01/2018
5	Insulin Resistance 01/2022 - 06/2014
4	Fibrosis (Cirrhosis) 01/2021 - 01/2017
4	Hyperemia 02/2011 - 01/2010
3	Hyperglycemia 01/2022 - 10/2015
3	Fatty Liver 01/2021 - 01/2017
3	Coronary Stenosis (Coronary Artery Stenosis) 08/2010 - 01/2010
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 01/2017
2	Cardiomegaly (Heart Hypertrophy) 10/2021 - 11/2013
2	Rhabdomyolysis 10/2021 - 01/2019
2	Reperfusion Injury 01/2021 - 01/2021
2	Inflammation (Inflammations) 01/2021 - 01/2017
2	Heart Failure 11/2020 - 06/2014
2	Necrosis 01/2019 - 01/2018
1	Weight Gain 01/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Hyperinsulinism (Hyperinsulinemia) 01/2021
1	Ischemia 01/2021
1	Iron Overload 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Weight Loss (Weight Reduction) 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Melanoma (Melanoma, Malignant) 01/2021
1	Experimental Melanoma 01/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Neoplasms (Cancer) 01/2021
1	Ketosis 11/2020
1	Body Weight Changes 01/2019
1	Muscular Diseases (Myopathy) 01/2019
1	End Stage Liver Disease 01/2018
1	Metabolic Diseases (Metabolic Disease) 01/2017
1	Glucose Intolerance 08/2016
1	Insulinoma 08/2016
1	Chronic Disease (Chronic Diseases) 04/2015
1	Body Weight (Weight, Body) 07/2014

Drug/Important Bio-Agent (IBA)

9	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2013
5	Insulin (Novolin)FDA Link 01/2022 - 07/2014
4	LipidsIBA 01/2021 - 07/2014
4	Monocarboxylic Acid TransportersIBA 11/2020 - 08/2016
4	Pyruvic Acid (Pyruvate)IBA 01/2019 - 06/2014
4	Oxygen (Dioxygen)IBA 08/2010 - 01/2010
3	Triglycerides (Triacylglycerol)IBA 10/2021 - 01/2021
3	DiglyceridesIBA 01/2021 - 07/2014
3	EnzymesIBA 01/2021 - 07/2014
3	Blood Glucose (Blood Sugar)IBA 01/2019 - 06/2014
3	Dipyridamole (Persantine)FDA LinkGeneric 02/2011 - 01/2010
3	Dobutamine FDA LinkGeneric 02/2011 - 01/2010
2	Alanine Transaminase (SGPT)IBA 01/2022 - 01/2018
2	lipineIBA 10/2021 - 01/2019
2	FructoseIBA 01/2021 - 01/2017
2	FatsIBA 01/2021 - 01/2021
2	2-acylglycerol O-acyltransferaseIBA 01/2021 - 07/2014
2	SugarsIBA 01/2021 - 01/2021
2	MonoglyceridesIBA 01/2021 - 07/2014
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2018 - 01/2017
2	MSDC-0602IBA 01/2017 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2013 - 11/2011
1	CollagenIBA 01/2022
1	Amino Acids FDA Link 01/2022
1	Fenofibrate (CiL)FDA LinkGeneric 01/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	2,4-thiazolidinedione (thiazolidinedione)IBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Heme Oxygenase-1IBA 01/2021
1	CateninsIBA 01/2021
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2021
1	honokiolIBA 01/2021
1	IronIBA 01/2021
1	Liraglutide FDA Link 01/2021
1	Glucagon-Like Peptide-1 ReceptorIBA 01/2021
1	Sirtuin 3IBA 01/2021
1	VLDL LipoproteinsIBA 01/2021
1	Antisense OligonucleotidesIBA 01/2021
1	NAD (NADH)IBA 01/2021
1	CarbohydratesIBA 11/2020
1	KetonesIBA 11/2020
1	NADP (NADPH)IBA 05/2020
1	Glutathione (Reduced Glutathione)IBA 05/2020
1	Peptide Hormones (Polypeptide Hormones)IBA 01/2019
1	Phosphatidate PhosphataseIBA 01/2019
1	Phosphatidic Acids (Phosphatidic Acid)IBA 01/2019
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2018
1	LigandsIBA 01/2018
1	Endocrine DisruptorsIBA 01/2018
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2018
1	CytokinesIBA 01/2018
1	Pioglitazone (Actos)FDA Link 01/2017
1	Trans Fatty AcidsIBA 01/2017
1	ThiazolidinedionesIBA 01/2017
1	CholesterolIBA 01/2017
1	Protein Kinase CIBA 07/2014
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 06/2014
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2013
1	HexokinaseIBA 11/2013

Therapy/Procedure

2	Liver Transplantation 01/2021 - 01/2018
1	Bariatric Surgery 01/2022
1	Immunotherapy 01/2021
1	Glycemic Control 01/2019
1	Therapeutics 01/2019